New kind of Depression Drugs found

How Psychedelic drugs work can be best understood by the fact that the brains of people have been tripping by consuming magic mushrooms. According to the British scientists, the conclusions drawn from this can be used to treat the patients who are suffering from depression. Two different studies were conducted regarding the effects of psilocybin that is the active ingredient found in the magic mushrooms and contrary to the expectations of the scientists, the results showed that the areas of the brain that are suppressed by the intake of anti-depression are the same areas that are dampened when the patients consume magic mushrooms.

“Psychedelics are thought of as ‘mind-expanding’ drugs so it has commonly been assumed that they work by increasing brain activity. But surprisingly, we found that psilocybin actually caused activity to decrease in areas that have the densest connections with other areas.” As said by David Nutt of the Imperial College of London. Mr Nutt gave a briefing about the studies on Monday. The regions of the brain, which are supressed, are called hub regions and they have been identified as playing the chief role in limiting our experiences of the exterior world and keeping it in order.
depression drugs

David Nutt said, “We now know that deactivating these regions leads to a state in which the world is experienced as strange.” The first study was published in the Proceedings of National Academy of Sciences journal. In the study, 30 volunteers were kept inside the magnetic resonance imaging scanners (MRIs) and the psilocybin was infused into their bloodstream. The MRI Scanner scanned the brain for changes in the activity. The result was that in the hub regions, the activity was found to be decreased. Many of the volunteers said that the sense of self-being was altered and they felt as if many cogs have been loosened.

The second study has not yet been published and is due on the Thursday in the British Journal of Psychiatry. This study involved only 10 volunteers and the result was that the volunteers found it easier to recollect personal memories. “We’re not saying go out there and eat magic mushrooms,” said Robin Carhart Harris from Imperial’s department of medicine. “But…this drug has such a fundamental impact on the brain that it’s got to be meaningful — it’s got to be telling us something about how the brain works. So we should be studying it and optimizing it if there’s a therapeutic benefit.”

New kind of Depression Drugs found
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