Tag Archives: aromatase inhibitors

Patients given exemestane show higher risk of Carpal Tunnel Syndrome

According to an international study in Lancet Oncology, the risk of carpal tunnel syndrome is higher in patients who suffer from breast cancer and are given exemestane than the patients who are administered tamoxifen. Aromatase inhibitors are more effective than tamoxifen in preventing breast cancer from recurring, but this is at the expense of side effects such as carpal tunnel syndrome. The study was aimed at studying and assessing the risk factors involved and the prognostic value of musculoskeletal symptoms in the course of treatment with the steroidal aromatase inhibitor exemestane or with tamoxifen after 2—3 years of tamoxifen.

Patients given exemestane show higher risk of Carpal Tunnel Syndrome
5 (100%) 4 votes

Exemestane increases Risk of Fractures in Cancer

Exemestane is a drug that is being commonly used to treat the cases of breast cancer in women. It belongs to a particular class of the drugs called as the aromatase inhibitors. Some of the breast cancers need estrogen to grow in the human body. Aromatase inhibitors are hence the drug that helps in inhibiting the synthesis of estrogen and hence this blocks the growth of cancers and lowers the estrogen levels. In spite of being so effective in dealing with the breast cancers it is also believed that the usage of this drug can weaken the bones in a woman. The women using this drug exemestane should hence get a regular bone monitoring check up done to evaluate the risks of fractures in the system.

Exemestane increases Risk of Fractures in Cancer
5 (100%) 8 votes