Compound Reference
& Category Guide

Overview: A powerful nootropic combination developed in Russia. Semax is a synthetic analog of ACTH (adrenocorticotropic hormone) fragments with potent cognitive-enhancing and neuroprotective properties. Selank is a synthetic analog of tuftsin with anxiolytic, memory-enhancing, and immune-modulating effects. Together they provide cognitive enhancement with anxiety reduction — a rare and valuable pairing.

Overview: N-Acetyl Semax is a modified form of Semax with an added N-acetyl group that significantly increases lipophilicity (fat solubility), enhancing blood-brain barrier penetration and bioavailability. The nasal formulation provides direct olfactory nerve pathway delivery to the brain — bypassing systemic circulation for more targeted CNS effects.

Overview: N-Acetyl Selank is an enhanced, more lipophilic form of Selank designed for superior nasal absorption and CNS penetration. It retains all of Selank’s anxiolytic and cognitive benefits with improved delivery efficiency. Particularly useful for anxiety management, stress resilience, and cognitive performance under pressure.

Overview: Intranasal NAD+ delivery provides a unique route for rapid brain uptake, taking advantage of the olfactory pathway to deliver NAD+ directly to the CNS. This formulation is particularly useful for neurological applications, cognitive enhancement, and situations where IV administration is not practical.

Overview: Intranasal glutathione delivers the body’s master antioxidant directly to the brain via the olfactory pathway. Glutathione is the most abundant intracellular antioxidant and is critical for neurological health — brain tissue is particularly vulnerable to oxidative stress, and glutathione depletion is implicated in Parkinson’s, Alzheimer’s, and other neurodegenerative conditions.

Overview: Methylene Blue is the world’s first synthetic pharmaceutical compound (1876) and has experienced a major research renaissance as a cognitive enhancer and neuroprotective agent. It acts as an alternative electron carrier in the mitochondrial electron transport chain, effectively bypassing damaged segments to rescue cellular energy production.

Overview: Testosterone Cypionate is a long-acting ester of testosterone and one of the most widely prescribed forms of testosterone replacement therapy (TRT) for men with hypogonadism (low testosterone). The cypionate ester provides a sustained release profile lasting 7–14 days per injection.

Overview: Testosterone Cypionate compounded with zinc combines standard TRT with zinc supplementation in a single injection. Zinc is an essential cofactor in testosterone synthesis and plays a key role in aromatase inhibition — helping to maintain the testosterone-to-estrogen ratio without the need for separate aromatase inhibitor medications.

Overview: Testosterone Enanthate is another long-acting testosterone ester with a slightly shorter release profile than Cypionate (5–10 days). It is one of the two most commonly prescribed TRT formulations and is functionally very similar to Testosterone Cypionate with minor pharmacokinetic differences.

Overview: Testosterone cream provides transdermal testosterone delivery through the skin, bypassing first-pass liver metabolism. It is used in both men (TRT) and women (for low testosterone symptoms) and offers a needle-free alternative with flexible dosing. Applied daily, it maintains relatively stable testosterone levels without the peaks and troughs associated with longer-acting injections.

Overview: Oral micronized progesterone (Prometrium) is bioidentical progesterone — identical in molecular structure to endogenous progesterone — in a micronized form that improves absorption. Used primarily in women for hormone replacement therapy, menstrual irregularities, and perimenopause/menopause management.

Overview: Transdermal progesterone cream provides topical delivery of bioidentical progesterone through the skin. It is used for perimenopause, PMS, cycle regulation, and as part of hormone balancing protocols. Cream delivery avoids the sedative first-pass liver metabolism of oral progesterone.

Overview: Progesterone troches are sublingual/buccal lozenges that dissolve in the mouth, allowing progesterone to absorb through the oral mucosa directly into the bloodstream. This route combines the rapid absorption of mucosal delivery with a metabolite profile between oral and topical administration.

Overview: Injectable progesterone in oil provides reliable, high-bioavailability progesterone delivery via intramuscular injection. This route is used when consistent, precise progesterone levels are required — particularly in fertility treatments, early pregnancy support, and cases where other routes have been insufficient.

Overview: Oral bioidentical estradiol in capsule form provides systemic estrogen replacement for women experiencing menopause, surgical menopause, or estrogen deficiency. Estradiol is the most potent and physiologically active form of estrogen, and bioidentical preparations match the body’s natural estrogen exactly.

Overview: Estradiol Cypionate is a long-acting injectable ester of estradiol providing sustained estrogen release over 1–4 weeks per injection. Used in gender-affirming hormone therapy and menopausal HRT when consistent, high-bioavailability estrogen delivery is preferred.

Overview: A combination injectable formulation providing both Estradiol Valerate (long-acting estrogen ester) and DHEA (Dehydroepiandrosterone) — the body’s most abundant steroid hormone and a precursor to both estrogen and testosterone. This combination addresses multiple hormonal needs simultaneously.

Overview: Bi-Est is a compounded bioidentical estrogen cream combining two natural estrogens: estriol (the weaker, protective estrogen) and estradiol (the potent primary estrogen) in an 80:20 ratio. This formulation mimics the body’s natural estrogen balance and is widely used in bioidentical hormone replacement therapy (BHRT).

Overview: Human Chorionic Gonadotropin (hCG) is a hormone that mimics LH (Luteinizing Hormone) at the LH receptor. In men on TRT, it is used to maintain testicular function, size, and fertility. In fertility medicine, it is used to trigger ovulation. hCG Pregnyl is the brand name for pharmaceutical-grade hCG derived from the urine of pregnant women.

Overview: Enclomiphene is the trans-isomer of clomiphene citrate — a selective estrogen receptor modulator (SERM) that blocks estrogen receptors in the hypothalamus and pituitary, causing the brain to increase production of LH and FSH, which in turn stimulates natural testosterone production. Unlike TRT, Enclomiphene raises testosterone while preserving fertility.

Overview: Anastrozole is a third-generation aromatase inhibitor (AI) that blocks the enzyme aromatase, which converts testosterone and other androgens into estrogens. Used on TRT to manage elevated estradiol (E2) levels that can cause side effects including gynecomastia, water retention, mood changes, and reduced libido.

Overview: DHEA (Dehydroepiandrosterone) is the most abundant circulating steroid hormone in the human body and serves as a precursor to both androgens and estrogens. Peak levels occur in the mid-20s and decline by up to 80% by age 70 — a decline closely associated with aging. Supplementation aims to restore youthful DHEA levels.

Overview: Oxandrolone (brand name: Anavar) is a synthetic anabolic-androgenic steroid with a very favorable anabolic-to-androgenic ratio. It is FDA-approved for weight gain after surgery, infection, or trauma, and for offsetting protein catabolism from prolonged corticosteroid use. In clinical practice it is also used for lean muscle preservation, fat loss, and anti-aging in appropriate patients.

Overview: Oxandrolone in sublingual troche form allows the compound to absorb through oral mucosa, partially bypassing first-pass hepatic metabolism. This may reduce liver enzyme elevation compared to swallowed oral tablets while maintaining anabolic efficacy.